How to Perform Dilutions
Once you have prepared the patient’s treatment vial (e.g., Red Vial), you will need to perform a series of dilutions before you begin treatment. Subcutaneous allergen immunotherapy begins with a small dose of a highly dilute allergen solution and, over time, increases in volume and concentration until the maintenance dose has been achieved.
For many practices, this involves a series of simple 10-fold dilutions. This typically involves four or five vials depending on the tolerance of the patient and the expected therapeutic starting point. Below is a table showing how to perform 10-fold dilutions that includes recommendations for labelling:
If you are using 5 mL vials instead of 10 mL vials, you can perform the same series of dilutions using the following strategy:
10-Fold Dilution - 5 mL Vials - 1:10 w/v Extact:
For more information see the following sections: