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Antigen

Any natural or synthetic substance capable of eliciting a cellular-signaling response. All allergens are ant

IgE

ns, but the reverse is not true. Ant

IgE

ns bind different classes of Ig receptors (e.g., IgA, IgG, IgM,

IgE

). Allergens specifically provoke an

IgE

antibody response (Type I hypersensitivity) in sensitized individuals, while non-sensitized individuals clear the allergen, typically symptom-free, via… read more 705357C1-B577-4332-A248-2D41FB183786Created with sketchtool.

Popular Topics

Home  >  Popular Topics Extract Formulations Extract Formulations Allergen extracts are available in a variety of formulations. An extract’s formulation directly impacts the stability of the allergenic proteins in solution and therefore the shelf life of the product. The FDA has determined maximum expiration dates for each formulation based on the estimated loss of potency… read more 705357C1-B577-4332-A248-2D41FB183786Created with sketchtool.

References

Home  >  References References General References Used Throughout Stability References Painful Injection From 50% Glycerin FDA Standardization Major Allergen And Standardization Regional Relevance Of Allergens Cross-Reactivity Management Of Anaphylaxis Coring & Syringe Technique Skin Testing USP 797 References – Beyond Use Date, Pharmacy Compounding Rules Allergen Information General References Used Throughout Cox, L, et al.… read more 705357C1-B577-4332-A248-2D41FB183786Created with sketchtool.

Major allergen

An allergenic protein that has been found to be clinically significant in over 50% of a population of patients allergic to that particular allergen. Major allergens have been characterized for a number of allergenic species. Common examples of major allergens include: Amb a 1 (Ragweed), Fel d 1 (Cat), Phl p 5 (Timothy grass), etc.… read more 705357C1-B577-4332-A248-2D41FB183786Created with sketchtool.