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Introduction
Glossary
Popular Topics
References
Basics of Extract Manufacture
Quality Parameters
Quality Concern – Color Variation
Quality Concern – Precipitation
Extract Formulations
Diluents & Preservatives
Formulation Concern – Alum
Formulation Concern – Phenol
Formulation Concern – Thiomersal
Formulation Concern – Glycerin Source
Potency Labeling
Standardized Extracts
Analytical Method – ID50EAL (“IDEAL 50”)
Non-Standardized Extracts
Major Allergen Characterization
Stability & Expiration Dating
Effect of Formulation on Stability
Effect of Dilution on Stability
Effect of Storage Conditions on Stability
What if my refrigerator breaks?
Expiration Date of a Mix
Selecting Allergen Extracts
Regional Panels
Ordering Supplies
Product Availability
Shipping & Receiving Extracts
Skin Testing Supplies
Skin Prick Test (SPT)
Intradermal (ID)
Positive & Negative Controls
Ancillary Supplies
Anaphylaxis Crash Cart
Quality Concern – Coring
Safety Concern – Latex in Rubber Stoppers
Importance of Cross-Reactivity
Latin Names & Major Allergens
Taxonomy – Grasses
Taxonomy – Weeds
Taxonomy – Trees
Oral Allergy Syndrome
Profilin & Pan-Allergens
Cross-Reactivity Among Non-Plant Allergens
Use of Allergen Extracts
Mixing Allergens
Aseptic Procedures & Sterility
USP 797 Compounding Guidelines
Mixing Concerns: Cross-Reactivity & Proteolytic Enzymes
Dosing
Dose Calculations for the Maintenance Vial
How to Perform Dilutions
Intradermal Dilutions
Dilution Tables
Warnings & Indications
Basics of Extract Manufacture
Quality Parameters
Quality Concern – Color Variation
Quality Concern – Precipitation
Extract Formulations
Diluents & Preservatives
Formulation Concern – Alum
Formulation Concern – Phenol
Formulation Concern – Thiomersal
Formulation Concern – Glycerin Source
Potency Labeling
Standardized Extracts
Analytical Method – ID50EAL (“IDEAL 50”)
Non-Standardized Extracts
Major Allergen Characterization
Stability & Expiration Dating
Effect of Formulation on Stability
Effect of Dilution on Stability
Effect of Storage Conditions on Stability
What if my refrigerator breaks?
Expiration Date of a Mix
Selecting Allergen Extracts
Regional Panels
Ordering Supplies
Product Availability
Shipping & Receiving Extracts
Skin Testing Supplies
Skin Prick Test (SPT)
Intradermal (ID)
Positive & Negative Controls
Ancillary Supplies
Anaphylaxis Crash Cart
Quality Concern – Coring
Safety Concern – Latex in Rubber Stoppers
Importance of Cross-Reactivity
Latin Names & Major Allergens
Taxonomy – Grasses
Taxonomy – Weeds
Taxonomy – Trees
Oral Allergy Syndrome
Profilin & Pan-Allergens
Cross-Reactivity Among Non-Plant Allergens
Use of Allergen Extracts
Mixing Allergens
Aseptic Procedures & Sterility
USP 797 Compounding Guidelines
Mixing Concerns: Cross-Reactivity & Proteolytic Enzymes
Dosing
Dose Calculations for the Maintenance Vial
How to Perform Dilutions
Intradermal Dilutions
Dilution Tables
Warnings & Indications
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USP 797 – Recent Updates and the Impact to Allergy Immunotherapy Compounding
September 1, 2020
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