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BAU

, Bioequivalent Allergy Unit. A potency unit used to characterize biological activity of select standardized allergen extracts. B

was defined using skin prick test titrations in a sensitized patient population. Reference standards were then established by the FDA and utilized by extract manufacturers to maintain the defined relative potency for the specific, standardized extract. This… read more

AU

A potency unit that expresses the relative biologic activity of an allergenic extract compared to an FDA-issued standard. House Dust Mite extracts are the only extracts that are standardized using

Alk OnDemand Education

Alk OnDemand Education Video Categories From Farm to Pharma & Allergy Extract Information From Farm to Pharma & Allergy Extract Information Collecting our pollens 2023-07-07 12:00 Frank Phillips, Collections and Crop Production Manager, discusses the progression of collection from trees and grasses to weeds Watch now Collecting our pollens 2023-07-07 12:00 × https://www.extractopedia.com/app/uploads/2023/08/AKODR23012_Farm-to-Pharma_1-Preparation-Overview-2021_PV10.webm Cleaning the… read more

Effect of Storage Conditions on Stability

Effect of Storage Conditions on Stability Allergenic extracts should be stored in a refrigerator when not in use. The proper storage temperature is 2-8°C (36-46°F). It is recommended to include a recording device in a refrigerator in order to monitor temperature and to note any deviations if they occur. In the event of a power… read more

Latest Topics

Home > Latest Topics Mixing Concerns: Cross-Reactivity & Proteolytic Enzymes Use of Allergen Extracts > Mixing Allergens > Mixing Concerns: Cross-Reactivity & Proteolytic Enzymes Mixing Concerns: Cross-Reactivity & Proteolytic Enzymes Some patients who present with numerous sensitivities may require treatment with a mixture of different allergens. In the United States, it is standard practice to mix… read more

References

Home > References References General References Used Throughout Stability References Painful Injection From 50% Glycerin FDA Standardization Major Allergen And Standardization Regional Relevance Of Allergens Cross-Reactivity Management Of Anaphylaxis Coring & Syringe Technique Skin Testing USP 797 References – Beyond Use Date, Pharmacy Compounding Rules Allergen Information General References Used Throughout Cox, L, et al.… read more

W/V

w/v, weight to volume. A ratio of the weight of dry raw material per volume of extracting fluid, expressed in grams per mL or kg per L. For example, 1:10 w/v implies that one gram of dry allergenic material (e.g. pollen) was extracted in 10 mL of extracting solution. A 1:20 w/v extract is half… read more

Systemic reaction

An adverse reaction to an allergen that affects more than the site of administration, typically the entire body (system). Examples include Urticaria (hives) and Anaphylaxis. read more

Standardized

An extract that has approved methods for measuring and assigning potency using an FDA standard reference. These extracts are labeled in Bioequivalent Allergy Units (B

), Allergy Units (

) and Amb a 1 (AgE) units. read more

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BAU

AU