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Dose Calculations for the

Maintenance

Vial Theformulabelowoffersasimplifiedmethodforcalculatingthevolumeofan extract to add based on the target dose selected. Importantly, thiscalculationcanbeusedforanypotencyunit(AU, BAU, PNU, w/v, or µg). V = 10T/E V: Volume to be drawn up from the manufacturer’s bulk concentrate and added to the patient’s vial T: Target

Maintenance

dose in 0.5cc injection (e.g., 2000BAU, 1000PNU, 7.5µg Der… read more

Home  >  References References General References Used Throughout Stability References Painful Injection From 50% Glycerin FDA Standardization Major Allergen And Standardization Regional Relevance Of Allergens Cross-Reactivity Management Of Anaphylaxis Coring & Syringe Technique Skin Testing USP 797 References – Beyond Use Date, Pharmacy Compounding Rules Allergen Information General References Used Throughout Cox, L, et al.… read more

How to Perform Dilutions Once you have prepared the patient’s treatment vial (e.g., Red Vial), you will need to perform a series of dilutions before you begin treatment. Subcutaneous allergen immunotherapy begins with a small dose of a highly dilute allergen solution and, over time, increases in volume and concentration until the

Maintenance

dose has… read more

Dosing One of the primary objectives when mixing allergenic extracts is to prepare a patient’s treatment set in a way that ensures an optimal therapeutic dose of each allergen in the patient’s allergen extract vial. Therefore, the limiting step when mixing is deciding what volume of each allergen to add to a patient’s

Maintenance

vial.… read more

Profilin & Pan-Allergens Cross-reactivity is often seen between unrelated species due to shared minor allergens such as Profilin. A minor allergen is an allergenic protein that has demonstrated clinical sensitivity in a minority of patients in a population. Common allergens that demonstrate clinical sensitivity across unrelated species are known as Pan-Allergens. Profilin is a structual… read more